Hi Steve, welcome back.
Unfortunately I don’t have any solutions for you, but didn’t want you to feel ignored. I’m on a Mac on R22 but experience the same annoying scroll wheel behavior that you do, so I pretty much avoid using it at all in C4D. As for the interface colors, I’ve tried a few times to look for particular ones but found the process painful and ultimately unproductive for the most part. It would definitely be nice if Maxon provided a way (perhaps a master list) to find the right one without so much trial and error. And again with that I’ve pretty much given up on adjusting any but the most basic ones (default object color, i.e.). Anyway, I hope you have better luck.