Definitely remove these from your Preferences:
LsManager.3.NumGPUs = 1
LsManager.3.GPUMapping = 0
LsManager.3.GPUMappingEnable = 1
System.Record.Lookahead = 5
These should not be required.
Of course, it’s impossible for us to say if the Hackintosh is causing the issue as we don’t test it or even support the GTX4xx cards on Mac.
Do you have a Mac Pro to test to see if you have a similar issue?