ProRes 422 HQ will give you a better start – less compression and better editing experience. Editing H.264 can be CPU intensive and re-compressing the H.264 can result in less than desirable results if you compress too much. However, you will quickly find out that keeping all that ProRes footage will soon fill hard drives, fast.
You will want to keep H.264 as your delivery video. Most people will be relying on Windows Media Player or consumer electronics to play back the video. Most will not play back ProRes video files. Plus, bitrate may be too much for many thumb drives.
So, if you think you will continue to have enough storage for ProRes files, I’d say go for it as a acquisition format. But, you may soon find out that storage will be your biggest problem.