Fixing an eyeglass reflection in one still image in photoshop is tough enough. After killing the camera operator, you have your work cut out as video is 30 still images every second and even a few seconds will take forever.
I would import one still frame into Photoshop, fix it, select just the fixed glasses, invert the selection, delete all but the glasses and import the .psd back into Premiere, overlaying it over the video and keyframing any motion/scale to match the video…this could be accomplished in your lifetime.