Just use exFat. It allows bigger files and works with Windows and Mac. Just keep in mind that if you format the disk in Windows the cluster size can’t be over 1024.
We have an imac with Adobe software and the Blackmagic Ultrastudio 3D thunderbolt I/O. I’ve had no problems controlling/capturing/editing to tape with HDCAM, HDCAM SR and DigiBeta decks.