Thanks for your help. I reinstalled Quicktime+Itunes, but that was not the issus. I had both video and audio clips that when played the audio would disappear and the video would as well. I am working with MOV’s.
I also tried playing the clips in Machina, this may be a seperate glitch but the audio played on the clip but the video would only appear when scrubbing.
What I ended up doing was deleting all of my Premiere Project and associated files. I then started a new project with the same settings, imported the files, and the clips were all correct. Interesting stuff. Anyway if you have any thoughts on the Machina glitch let me know. Thanks for your help.