When booted from the Mac OS you can copy off a NTFS drive but you cannot write to it. So no saving back to that drive.
Both Windows and Mac can fully reed and write to a Fat32 drive, but there are severe limitations to using that format (speed, file size, and file name limitations).
I have heard that there may be a 3rd party software out there that will allow the Mac OS to write to a NTFS drive but I do not know what is is called.