Basically it boils down to this:
When it’s being shown on the interwebs it’s being re-encoded by the service and you have no power over that. The color will also change depending on what browser and OS the viewer is using. Software based changes are in 99 % of the cases player based problems that you also don’t have any say over. Also probably 99 % of the viewers of your stuff are looking at this without a calibrated monitor.
Life’s too short for trying to control things you have no say over so I grade everything to a specification and when it’s out of my hands then that’s that.