Hi Lukas, for video settings I would render in .MP4 (scroll down in the render box to MainConcept AVC/AAC and select Internet 1080 and click customize template) check 1920×1080, Keep the audio sample rate at 96,000hz and 320,000bps. As you have an Nvidia card, I would also enable GPU accelerated rendering which will speed up the whole process. These are the settings I use whenever exporting for an internet upload. The file size should be quite reasonable. I think YouTube also takes advantage of the H.264 codec so upload speeds should be quicker as well.