Wire removal is incredibly easy to do in post and actually made simpler if the wire is fairly clear and obvious in the initial footage. All you need is a plugin which you can find for whatever compositing software you use through Google.
If you wish to do it in camera best way to go is put the wire on opposite side of the actor’s body from camera and be careful in how it’s shot and framed. For quick edits you can get often away with bloody murder.
Noah