Chris,
I don’t count myself an aficionado with Compressor but maybe I can offer my thoughts?
My caveat: I have 5 drives and two servers connected to my system though I rarely burn to DVD or Blu-ray.
I duplicate my setting for a client, rename it for a specific purpose and make the necessary adjustments. After which, I choose the “DESTINATIONS” tab in the Settings dialogue and set that destination there, IF I know I will be using this repeatedly.
IF, I need to send it to another destination then I can overwrite this default setting by; after adding the project to the batch dialogue, then your setting to it, right-click the “SOURCE” field. In the drop down, choose “DESTINATION” and then, “OTHER” from the contextual dialogue box. (See attached image)

This is, of course going on the assumption that the setting has not been configured to a DVD/Blu-ray destination to begin with and that I am not talking twaddle.
Either that or you can simply set up a DROPLET on your desktop, therefore bypassing the whole of Compressor’s UI.
HIH,
Lawrence