A single USB drive is not good. Not good at all. Get a RAID. An USB 3 RAID. Or Thunderbolt RAID, which is much better.
Edit Ready costs only $49. It does a great job of transcoding or rewrapping your files. I love ER. You’ll have to spend a bit of money, you just have to. And that would save you a lot of time and headache.
You’ll have to learn quite a bit too. Like how to differentiate between USB2 n USB3.
Caldigit, GTech, Owc make USB3 RAIDS and Thunderbolt RAIDs. I’ve used all of these and am currently using Promise Pegasus Thunderbolt RAID.
Spend a bit of money now to save yourself a LOT of trouble later:)
K