The PhotoJPEG codec can’t do lossless – even at 100% quality it is a lossy codec. At 100% quality only it is a 4:4:4 codec and at 99% and below it is a 4:2:2 codec.
PhotoJPEG at 100% is 4:4:4 lossy
PhotoJPEG at 99% and below is 4:2:2 lossy
Jpeg2000 at 100% is lossless (but uses lots of CPU power)
Animation at 100% is lossless 8 bit
PNG is lossless too btw, but in the quicktime container it handles only 8bpc too.
PNG at 16bpc can be good for images sequences.
I compared TGA, PNG, and TIff to PSD and only Tiff(lzw off) at 3200% was flawless in comparison in RGB color picker values.
TGA, PNG, and Tiff (only with LZW compression on) seem to have strange micro pixel color changes at 3200%. I’m guessing LZW has coding precision rounding errors in the area of a millionth of a rgb value.
PSD and Tiff(LZW off) are perfectly lossless but since Tiff is half the size, that’s what I use.
I would love to hear other people’s roundups of video codecs.