Like i said, izotopes de click function is designed to remove short spikes. Also, are you trying to do it in say Pro Tools or in a video NLE (as they only offer a very crude 1 25th sec edit whereas a sound nle like pt goes much tighter.
You could try setting up a ducker to be triggered off the high ampolitude audio spike that goes right down to zero, but whose attack and releaase are very fast, hence autotriggering the duck?
If its not in your skillset , Im sure theres a local post studio who will have the neccessary skillset in house?
Peter
Post Production Dubbing Mixer