I have been teaching Premiere 2 on about 20 different PCs in the last few months, including some dual Zeons, 3.4 ghz, 4 GB RAM, 1 Tb Raid and the issues I see are on occasion some function/command will just stop working and restarting the PC fixes that. We did have one occasion to use the Auto saved version of the Project.
Also Pro and Elements crash when trying to burn DVDs, although Encore can.
I would update video and sound card drivers with vendor versions, failing that, update the BIOS.