Codec playback performance is not only about the codec itself, but the drive system, how it’s connected, etc. which usually leads most projects to transcoding to DNxHD. And even then the above will have an impact.
That aside, how are you planning on finishing? Where is color correction going to be done? Will it be round tripped or finished in a color correction or other type system? What is the delivery format?
These answers will help define a workflow.
Michael