Yes, definitely possible. In fact, should be pretty easy. The sky is very clearly separated from the flowers. I would mask the buildings, so that you just need to create a matte to separate the moving flowers and the tree from the sky. Probably one of the RGB channels will work well for that.
Important to choose a very wide angle sky image — you can see the horizon and the zenith at the same time, so this might be a 120 degree FOV — and match the perspective so that it looks like it belongs. Since it looks like it is windy, the clouds could be moving. With a still image of clouds I often use the slant effect and keep the horizon in place to create moving clouds. Or find or shoot a wide angle sky video to put in there.
Kalleheikki Kannisto
Senior Graphic Designer