Hi Keith,
Thank you for your reply!
I’m using After Effects CS5 on Win 7 x64.
I’ve attached a screen grab of the settings explained in my first post:

I had a closer look at all my DNxHD files and noticed that compared to the ProRes originals there is a very slight noise softening that is just appreciable at around 800% zoom. This fact though, should affect both A2 and B2 equally.
I also realised that video A contains a slightly higher proportion of areas of near solid colour (eg a clean painted wall) compared to video B (eg containing a bush). Could this really attribute to near 50% compressibility?
Below is a list of all the other compression tests I’ve run to try to make sense of this puzzling situation.
ProRes originals (I suspect they were originally 8bit but supplied to me saved as 10bit, unsure how to check):
* A1 = 1800MB (zipped: 1791MB) (approx. 0.5% compression)
* B1 = 2010MB (zipped: 1985MB) (approx. 1% compression)
DNxHD: (only 100 frames compressed for speed)
* A2: 8bit prj – output depth-millions – 1080p/25 DNxHD 185 8bit = 90.5MB (zipped: 49MB)
* A3: 16bit prj – output depth-trillions – 1080p/25 DNxHD 185 10bit = 90.5MB (zipped: 60MB)
* A4: settings as with A3 but 100f are from different point in video = 90.5MB (zipped: 41MB)
Strangely A4 zips better than A3. Both have locked off cameras but A3 has two moving actors in shot compared to A4 only having one actor moving in shot.
* B2: 8bit prj – output depth-millions – 1080p/25 DNxHD 120 8bit = 59MB (zipped: 58.5MB)
* B3: 8bit prj – output depth-millions – 1080p/25 DNxHD 185 8bit = 89.5MB (zipped: 88.5MB)
* B4: 16bit prj – output depth-trillions – 1080p/25 DNxHD 185 10bit = 89.5MB (zipped: 88.5MB)
Graham Macfarlane
3D animator and VFX specialist
London UK