I’ve been on DS since late 1999. It has come a long way in conform from MC. I tried smoke in 2011, but couldn’t really afford the time to learn it before a new job was to begin, so i stuck with DS. We have done conforms from MC and FCP (using duck or boris) to ds, and even the FCP confroms have gotten better.
With a MC to DS conform you can either send a list and re aquire your footage from source material, or you can simply use the DNXHD media in both applications.
I use Red footage in DS quite a bit. The workflow from MC to Red, going from an offline res to a full HD, 2k or 4k resolution is very very good. Including very easy reformatting of frame size, or different color versions of the same shot.
In my limited experience with smoke, i found the editing side of things horrible. I know the idea is to edit with MC, and conform with another tool, but there are always time when you have to do something in the online suite. I also found the CC tool on smoke to be lacking a bit. A guy who used to work for us and is now on his own, started with smoke, but quickly added Lustre for better CC control.
I know some of that is supposed to have change for their newer version.
As for hardware, DS isn’t really on dedicated hardware anymore. Its the same idea as smoke. You have to buy a qualified computer. Mac for smoke, PC for DS. I’m assuming you aren’t going down the linux version of Smoke. You also need some qualified hardware. Specific graphics card and Kona hardware for DS- not sure what smoke is qualified with anymore.
Also good to note that DS comes with a free license of Media Composer- so there is a savings right there.
Glenn