LTO is a tough one and it really depends on your needs. As a low end solution you could consider getting a SCSI card and a run an LTO -3 or LTO 4 at less cost.
Compatibility and future proofing is a concern. Quantum has been making LTO for a long time and offer internal and external drives. Research the software available to write the archives.
I’ve seen it done a bunch of ways from low to high end, but it’s best to first define your needs and the kind of volume you will be dealing with.
The system Gary mentioned is an excellent solution for broadcast and post houses who need to back up a lot of data on a daily basis.
For lower volume consider quantum and SCSI card to keep costs down. Buy high quality tapes in bulk and make two tapes of each archive or run the complete verification if you only write one tape.
David
Peace