I guess so, transition is complicated as sometimes it works fine with twixtor. If everything is sliced you might as well switch to Mode No MV for these.
If you can find a way to visually mark the layers easily then you have a way to split in two big paste. For example just twirl open the ones with transition to remember then I think if you make in one copy of twixtor the menu Quality animatable, you can cut the value “no MV”, reset it to Best, then you can I think select all the layers you want to set to that and just paste (provided Twixtor is already in layer). I just tested this with the public beta, seems to work.
Also if you start with a layer and you put Twixtor setup correctly in it, each time you split the layer it copies Twixtor,
Pierre