I’m not sure what OS you are running. Try downloading the latest AJA desktop video driver software.
https://www.aja.com/products/io-4k-plus#support , 17.1.3 ,
The instructions I posted above were to correct a faulty software not recognizing the device.
I downgraded after that to Catalina for a more stable system. (Intel macpro cheesegrater.) haven’t upgraded since.