Thanks for you help.
The results of my experiments are attached:
Top left original 8 bit per channel project file.
Top right default saving as a 16 bit file (1555)
Row 2 left red 255 black gradient saved as 565
Row 2 right green 255 black gradient saved as 565
—— you can see the different one bit makes with the green
Row 3 left blue 255 black gradient saved 565
Row 3 right green 255 black gradient saved 1555.
It is interesting (to my eyes) the banding seems less pronounced with the blue gradient. If I remember blue is not the most sensitive colour for human eyes.
The greyed out options become active if you add an alpha channel.
Quite useless actually as the RGB is reduced to 444.
Obviously what I need is a piece of software that would allow 646, which would probably correct fro the original colours orange and blue
