I am having the same issue as well and desperately need to resolve it. I was adding an effect just fine, then went to add an additive dissolve plugin to a clip and then the hand with the slash sign appeared. now whenever I even just grab an effect plugin I see this hand and needless to say can’t apply it to any clips. I am fairly new to premiere but this seems like a quickly solvable issue I just have no idea what went wrong. clips are active and everything.