honest opinion here, so strap yourself in and prepare for constructive criticism 🙂
you wanted a “vibrant / cinematic film, but with an universally realistic and natural feel and tone”
those 2 statements are at odds. Cinematic is usually tinted or off-white. Never calibrated to, let’s say, a bland news broadcast color palette.
bumping up saturation to 100% in any NLE will bring an unnatural neon glow that burns all the similar tones into one glowy mush. There are many ways to bring out color than pure saturation, such as contrast, tints, white balance, luma mattes etc.. The leave color effect is one good example, others; channel mixing, or even variations of hue of individual colors, or even hints of technicolor.
I recommend a little more experimentation, and don’t rely 100% on lumetri. It doesn’t have 10% of what’s out there.