Certainly it’s possible, but stopping down that much has side effects. When you go past f16 to like f22 the focus will be deep, but the whole image will be soft. On one film I shot with a wide lens stopped down for deep focus I imported the footage only to find that the whole thing was blurry! So keep that in mind and decide what your priorities are (deep focus with soft image vs. more shallow focus with sharper image). Also, the small aperture will reveal ANY dust, hair, dirt or smudges on your lens and sensor, so make sure both are nice and clean.