Thanks for all the advice. I am speaking of a shot as a setup AND an edit. While the occasional shot may repeat, for most part every new edit would be a change of camera position.
As far as compositing in a 3D program, I wasn’t intending to do anything as intricate as that. The idea is to shoot everything practical, no CGI. Meaning I would be shooting the room with a green screen ceiling, and then building the extension in another room and matching camera angles. So if I was shooting waist high towards the ceiling in the green screen room, I would be shooting ankle high in the false ceiling room, and compositing that into the green screen where the ceiling should be. I wanted to get an idea mostly of the practicality of doing this, obviously I will have to keep meticulous notes on the type of lenses used, angle of tilt on the tripod, and position of the camera in the room from shot to shot.
Workflow-wise, this would all be shot on a Red Scarlet, using DPX files, then edited in Final cut on an iMac before compiling the final shots in after effects, or some other program.
The main reason for doing it this way is budget and time. I would rather find a soundstage and construct a set, but I don’t have a lot of luxury money-wise to rent a real one, and pending finding some large enclosed space I can occupy for an extended stretch of time for a limited amount of money, this seems to be the most practical way of doing this.