Hello Foy Watson,
You can disable OpenGL in CS5-down. However, this is not possible with CS6-onward. But there are ways to disable Advanced OpenGL, which might help you with any issues you are experiencing with if you are using never versions of After Effects.
I suggest reading this thread on the Adobe Forum’s. I posted a reply that you might want to check out on here:
https://forums.adobe.com/thread/1030251