3 GB is 3,221,225,472 bytes. For 100 minutes using 192kbps audio encoding with a 5% file size safety margin, then you would use 2-pass VBR with the following parameters:
Minimum = 2,328,000
Average = 3,888,000
Maximum = 6,800,000
If you mean you want exactly 3,000,000,000 bytes instead of 3 GB (again with a 5% safety margin), then use the following:
Minimum = 2,160,000
Average = 3,608,000
Maximum = 6,312,000
Vegas uses exact bits when entering the encoding bitrate, other encoders used KB which is 1024 bits per KB instead. The numbers would be slightly lower in this case.
Since it’s mostly talking heads, it should end up looking pretty good. If it had a lot of motion in it, trying to squeeze 100 minutes of HD into 3GB might end up look a little ragged. Regardless, you definitely want to use 2-pass VBR, the render will take longer but will absolutely be worth it.