I have Windows 7 as my main box, but I don’t think I’ve gone to 12.3 yet.
I do have Windows 10 on a laptop, and will tell you cs6 runs on it, but I do have to run AE and Premiere Pro in Win 7 compatitbility mode.
Photoshop seems to be fine, so It must have something to do with a video element. The good news is you set up compatitbility mode once, and then forget about it.
FWIW, the only problem I’ve had issues with is MacDrive 9 Pro, which does not work in Win 10, and doesn’t seem to have the ability to run in any kind of compatitbility mode.
Glenn