I think we need more info. Is your pre-comp the same length as the comp it’s nested in? If so, you have to set some keyframes around the area you want to loop and delete the last one that AE added when you turned on time remapping.
If your pre-comp is shorter than your main comp and you want to loop the entire pre-comp, after you enable time remapping you have to extend the duration of the pre-comp with the little slider gizmo, set a keyframe at one frame before the last keyframe that AE added and change the value of the last keyframe to zero to get a perfect loop. I’m assuming you’re using the “cycle” flavor of loopOut().
Dan