No, not that I know of. AE will only clear the execution stack of scripts after they are done and there is no explicit release function. It does so because basically when running a script all other AE internal functions are “on hold” and only wait to be called by a script. If it’s an option, you may consider splitting up the data files and load them in in separate chunks. Depending on what type of data you handle, you may also want to consider Digital Anarchy’s Data Animator plugin – I’ve fired large data sets on it for testing purposes and it worked just fine. It’s no speed demon and has its limitations, but it might help you if you do this type of work quite often.
Mylenium
[Pour Myl