You may have to re-create the graph in Photoshop (unless your client has a psd version with separated layers).
You can’t really isolate the colors – if you key the colors they won’t simply disappear in your image, they will actually cut a hole in your image – revealing black. So you really need to recreate your graph I think.
Of course, there may be other workarounds. If its a bar graph, you could also reveal the bars by using a moving color solid layer. It might be easier (instead of recreating the graph w/ separate layers) to create a sort of mask that has the same color tone as your graph background layer. So long as you don’t have a gradient, texture, or a multicolor background this should work. Just set up keyframes to reveal through cropping or position changes.
Hope that makes sense.