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Mercury Playback Engine Would NOT Work Until I Tried This…
Thought I’d post a solution to what I was trying to figure out. Yesterday I realized that the Mercury Playback Engine selection in Premiere Pro CS5 was greyed out and not enabled. So I Googled everywhere, updated all kinds of drivers, made sure my Premiere was current, etc. double checked that my card (Quadro FX 3800 1GB) was listed in the CUDA Supported Cards file (of course it was), and so on. All good to go, but still no Mercury.
Finally, I used the gpusniffer.exe (described here for another use: https://blog.krama.tv/hacking-adobe-premiere-cs5-to-enable-more-nvidia-cuda-cards/) to see what was going on and it was as simple as disabling my Tesla card, which Premiere was reading before the Quadro. So give that a run and maybe your multiple graphics cards or a Tesla are in the wrong order for Premiere’s liking! Hope this helps someone.