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lossless 4x smaller does exist!
If you have done lossless work, you know it takes up a lot of space. JPEG 2000 can be set lossless and is 4 times smaller than animation, supports millions+ alpha.
Resolutions of 8192×8192 Pixel (e.g. 4096×3112 for 35mm Film Scans)
Colorspace: sRGB, SRGB-YCC
Number of color components: 3-4 (e.g. RGBA)
Bitdepth: 10-16 Bit/color component
Pixel Sampling: 4:2:2 – 4:4:4
Compression types: mathematically lossless, visual lossless, lossyhttps://www.jpeg.org/apps/cinema.html
https://www.jpeg.org/public/DCINEMA-v2.pdf