I’ve seen this before… …a re-he-healy long time ago. Thought this type of problem was dead and gone. It was with a lot smaller audio files then, but it did happen a lot more then.
Several possible causes:
1. Different audio output modules and gfx hardware (if they are the same, check the configuration and the firmware on them for differences; as newer adobe software is still having CUDA and Mercury issues with some cards; make sure your output card has the same capabilities for sample rates as your sequence; you may want to RE-render just that part of the work area on that machine to be sure).
2. Like I said above, make sure your sample rates for audio output device is the same as your sequence (though this is usually handled by emulation).
3. IF the output devices or wires are receiving undue EM interference, you will have problems. Can also happen with power-shorting (sometimes a power outlet plug will have a bad ground or something, and it can affect certain reads from an external drive). Check your USB cord for breaks. Are there other devices being heavily accessed at the same time with plugs close by?
If it sounds like a digital distortion where the sound seems broken up, it has to do with the data read from the drive, more than likely. This is a result of both hardware and software load on the machine, along with the configuration of the output modules. This means if one machine uses a specific config and another machine doesn’t have the same exact hardware, you will have problems like this. IF it’s the same location over and over, every single time, you are dealing with a file problem, again tied to the read speed of that particular file. Try a defrag. Try a disk check. Hit and miss on this one.
Sometimes, setting the drive close to other sources of EM can corrupt a read or scramble it in the wire. This will have the audio scramble up at different points each time. The same would be true of a bad usb wire or port on that machine. Try different ports.
If the physical hardware of each machine is different, especially the output hardware, you’ll occasionally get audio that cannot be re-sampled down. That audio will come out distorted. Try using USB output hardware with 96k or above sample rates for output. These have advanced drivers that can sometimes do a better job. Try a dedicated audio card with extremely high sample rates. Basically, try to match hardware as much as possible. If that isn’t feasible, create a new sequence matching the video size of your primary, then set the audio to a lower sample rate and NEST your primary into it. Other machines with lower audio specs will be able to play through this sequence.
That’s all I got… I can’t think of any other reason accept a bad port, a bad interface in the offending computer, or the peaks are too high to be output correctly.