Yes, it’s possible. Both in Photoshop and in ImageReady. I think that ImageReady may even have more features for creating droplets — that’s what these batch jobs are called by Adobe.
Anyway,
* open a picture,
* open the “History/Actions” window (may already be open), go to Actions, create a new Action.
* press Record Button, and then resize the picture to your liking. Press Record again to stop recording
* File, Automate, Create Droplet, select your droplet and save it.
You can also later specify droplet settings like where to save the resized image and tweak other options.
I’m somewhat going by memory here, you may have to tweak and play with the settings to get it working right.
If this won’t work in Photoshop, try ImageReady, it may be easier there.