It depends on the footage and your delivery requirements. I would probably start with a resolution of 1280×720 and 1:1 square pixels. The choices for managing frame rate are as follows:
– Insert clips directly onto the timeline; Premiere Pro automatically drops every fifth frame of the 30fps footage or repeats every fourth frame of the 24fps footage
– Enable frame blending; Premiere will overlay neighboring frames to smooth the motion
– Slow down or speed up the clips; note this can create issues with audio pitch or synchronization
– Interpolate new frames using After Effects
I recommend creating a timeline at each frame rate and testing a few clips to see which approach works best. Also, how will the delivered file be displayed? Most monitors and projectors refresh at 50Hz or 60Hz based on the input power frequency.