I use transformers to power my 110 lights in my 220 house in Germany. I haven’t experienced any noticable affect to the lamps themselves, but I agree with the other post that they are bulky and heavy (like a car battery).
If you are talking about fluorescent lighting, they flicker at whatever hertz you are using, so a 50Hz socket will cause the lamp to flicker at 50HZ, which looks awful on U.S. cameras shooting at 60fps. You can mask this in-camera by setting the shutter to 1/00th sec. but this eats about a stop of light.
If you are using halogen lights, its probably much easier just to buy 220 version bulbs and simple plug adapters.